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TB500 5mg

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Thymosin Beta-4 is a 43 amino acid peptide sequence. In animal models, Thymosin Beta-4 has been shown to improve blood vessel growth, regulate wound healing, decrease inflammation, and reduce oxidative damage in the heart and central nervous system.

Thymosin-beta-4 has a role in protection, tissue repair, regeneration and remodeling of injured or damaged tissues. It is also of active interest in anti-aging research.
Where to buy TB-500 5mg? Shop now for TB-500 5mg with exceptional quality and get more for less with our bulk sales. Quick 48-hour delivery available.

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    Properties

    TB-500 5mg 

    Chemical Formula: C38H68N10O14
    Molecular Mass: 889.01g/mol
    Synonyms: Thymosin Beta-4 Acetate
    CAS Number: 885340-08-9
    PubChem: 16132341
    Total Amount of the Active Ingredient: 5 mg (1 vial)
    Shelf Life: 36 months


    Uncompromising Quality Assurance for TB-500

    At Triggered Brand, we are dedicated to providing researchers with high-purity TB500 that meets the strictest quality standards. Products listed on our site undergo a rigorous quality control process to ensure reliability and consistency for your research.

    1. Receipt and Inspection: Upon receiving TB500 from our trusted supplier network, we perform a preliminary quality check to ensure the product meets baseline specifications.

    2. Purity and Assay Testing: Before products are listed for sale, they undergo third-party purity testing to confirm the percentage of the active compound and assay testing to verify the compound’s concentration.

      • Purity Testing: Determines the level of impurities or contaminants in the product, ensuring it meets research-grade standards.
      • Assay Testing: Confirms the compound’s chemical composition and potency, verifying its suitability for experimental use.

    3. Testing Methods: Our testing partners use advanced analytical techniques, including:

      • High-Performance Liquid Chromatography (HPLC): Analyzes purity by separating and quantifying individual components in the compound.
      • Mass Spectrometry (MS): Identifies the molecular structure and verifies the compound’s identity.
      • Fourier Transform Infrared Spectroscopy (FTIR): Confirms the compound’s chemical bonds and functional groups.
      • Nuclear Magnetic Resonance (NMR): Provides detailed structural analysis of the compound.

    4. Approval for Sale: After these tests return positive results we list TB500 5mg on our site for purchase. This ensures you receive validated research-grade products that you can trust for your experiments. Lab tests are occasionally published on the website.


    Scientific literature

    Synthesis and characterization of the N‐terminal acetylated 17‐23 fragment of thymosin beta 4 identified in TB‐500, a product suspected to possess doping potential

    Abstract
    The formulation TB-500 is suspected to be used as doping agent in sport. This work describes the detection and the identification of the N-terminal acetylated 17-23 fragment of human thymosin beta 4 (Ac-LKKTETQ) in TB-500 by means of high-performance liquid chromatography/high resolution mass spectrometry using an Orbitrap Exactive benchtop mass spectrometer. Ac-LKKTETQ was also synthesized by solid-phase peptide synthesis, and an analytical strategy for detection in plasma and urine by high-performance liquid chromatography/low resolution triple-quadrupole mass spectrometry was suggested.

    Adsorption effects of the doping relevant peptides Insulin Lispro, Synachten, TB-500 and GHRP 5

    Abstract
    The tendency of peptides to adsorb to surfaces can raise a concern in variety of analytical fields where the qualitative/quantitative measurement of low concentration analytes (ng/mL-pg/mL) is required. To demonstrate the importance of using the optimal glassware/plasticware, four doping relevant model peptides (GHRP 5, TB-500, Insulin Lispro, Synachten) were chosen and their recovery from various surfaces were evaluated. Our experiments showed that choosing expensive consumables with low-bind characteristics is not beneficial in all cases. A careful selection of the consumables based on the evaluation of the physico/chemical features of the peptide is recommended.

    Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro

    Abstract
    Background: TB-500 (Ac-LKKTETQ), derived from the active site of thymosin β4 (Tβ4), has various biological functions in its unacetylated form, LKKTETQ. These functions include actin binding, dermal wound healing, angiogenesis, and skin repair. The biological effects of TB-500, however, have not been documented. And the analysis of TB-500 and its metabolites have been neither simultaneously quantified nor structurally identified using synthesized authentic standards.

    Methods: This study was aimed to investigating simultaneous analytical methods of TB-500 and its metabolites in in-vitro and urine samples by using UHPLC-Q-Exactive orbitrap MS, and to comparing the biological activity of its metabolites with the parent TB-500. The metabolism of TB-500 was investigated in human serum, various in-vitro enzyme systems, and urine samples from rats treated with TB-500, and their biological activities measured by cytotoxicity and wound healing experiments were also evaluated in fibroblasts.

    Results: The simultaneous analytical method for TB-500 and its metabolites was developed and validated. The study found that Ac-LK was the primary metabolite with the highest concentration in rats at 0-6 h intervals. Also, the metabolite Ac-LKK was a long-term metabolite of TB-500 detected up to 72 hr. No cytotoxicity of the parent and its metabolites was found. Ac-LKKTE only showed a significant wound healing activity compared to the control.

    Conclusion:The study provides a valuable tool for quantifying TB-500 and its metabolites, contributing to the understanding of metabolism and potential therapeutic applications. Our results also suggest that the previously reported wound-healing activity of TB-500 in literature may be due to its metabolite Ac-LKKTE rather than the parent form.


    TB500: Dosing and Mixing for Research 

    Choose the Right Format: Vials or Capsules

    TB500 is available in: 

    Offered in 5mg10mgBPC157|TB500 5mg/5mg blend, as well as bundles to save you money: BPC157 5mg|TB500 5mg Bundle, and BPC157 10mg|TB500 10mg Bundle, vials provide flexibility for researchers needing custom mixing solutions or multiple administrations.

    Researchers should select the type and size that align with their study objectives and experimental needs.

     

    Mixing TB500 Vials

    Proper preparation is essential for research accuracy and consistency. Researchers typically use one of the following solutions for mixing:

     

    Sterile Water for Injection:
    Commonly chosen for single-use applications, sterile water ensures purity and minimizes contamination risks. Researchers often use sterile water for single-dose studies or where absolute sterility is paramount.

    Bacteriostatic Water (BAC Water):
    Containing 0.9% benzyl alcohol to inhibit bacterial growth, BAC water is ideal for studies requiring multiple administrations over several days or weeks. Researchers value BAC water for its stability in ongoing research.

     

    Understanding Dosing for TB500

    When conducting research with TB500 5mg Vial, it is crucial to recognize that dosing parameters vary based on the specific objectives and design of each research study. Research compounds, including TB500, are intended strictly for in vitro testing and laboratory experimentation purposes and are not approved for human consumption.

    In accordance with legal and regulatory guidelines, we cannot provide dosing guidance or recommendations for TB500 5mg Peptide Vials. Providing such advice would violate compliance laws, as it could be interpreted as prescribing usage for research studies.

    This product is not a drug, food, or cosmetic and must not be introduced into humans or animals under any circumstances. It should only be handled by licensed, qualified professionals in a controlled research environment.

    For information regarding dosing, researchers are encouraged to consult peer-reviewed studies or other reputable scientific sources relevant to their field of study.


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    Disclaimer

    The information provided above is not intended to substitute medical advice, diagnosis, or treatment. Should you have any questions regarding a medical condition, seek the advice of your physician or a qualified healthcare provider. In no case should medical advice be disregarded or delayed because of what you have read or seen. We bear no responsibility or liability for your use of any of our research compounds and products. Please note that they are being sold for research purposes ONLY. We do NOT condone any personal use.

    Note: In some cases wherein the assigned top colors are out of stock, a different top color will be used to ensure that your order will not be delayed. Should you need assistance identifying the peptide vial that you received, please send us an email at [email protected].

    ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.

    The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: “in glass”) are performed outside the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat and/or cure any medical condition, ailment or disease. Bodily introduction of any kind into animals or human is strictly prohibited by law.

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    FAQ

    TB 500 5mg Vials  

    How to reconstitute TB 500 5mg vials?

    TB 500 5mg vials contain a peptide powder, which is typically a puck or loose bits due to shipping. To reconstitute a TB 500 5mg vials, researchers typically use bacteriostatic water, combining it with the peptide powder according to the specific requirements of their research protocols.

     

    How to dose TB 500 5mg?

    The dosing of TB 500 5mg in vials form will vary according to the experiment being conducted. We do not provide dosage recommendations as our products are intended for research purposes only.

     

    How to administer TB 500 5mg?

    There are multiple methods of administering research products that are under investigation in various studies. The choice of administration technique should align with the specific goals and design of the researcher’s study. We provide products solely for research use, we do not offer advice on administration methods.

    This is the extra content added to the product description.